A reader just commented on this so this is a quickie article to debunk this “tweak”.
The “tweak”
-set autotuninglevel=disabled
-default setting = netsh int tcp set global autotuninglevel=normal
-to check your setting Open Admin Command Prompt and enter netsh interface tcp show global
-disabled = Open Admin Command Prompt and enter netsh int tcp set global autotuninglevel=disabled
-return to default = Open Admin Command Prompt and enter netsh int tcp set global autotuninglevel=normal
-This setting does not require a reboot.

Aug 17, 2016 How to disable ‘Window Auto-Tuning’ on Windows 10 Use the Windows key + X keyboard shortcut to open the Power User menu and select Command Prompt (Admin). Type the following command and press Enter: netsh int tcp set global autotuninglevel=disabled.
Check the State or Current Setting of TCP Receive Window Auto-Tuning. Open elevated command prompt with administrator’s privileges. Type the following command and press Enter: netsh interface tcp show global. The system will display the following text on screen, where you can check on the Auto-Tuning setting: Querying active state TCP Global Parameters.
To do this, follow these steps: Click Start, type regedit in the Start Search box, and then press ENTER. Locate and then right-click the following registry subkey: HKEYLOCALMACHINESoftwareMicrosoftWindowsCurrentVersionInternet SettingsWinHttp. Point to New, and then click DWORD Value.
THE INFORMATION IN THIS ARTICLE APPLIES TO: All Windows products; DISCUSSION. Tuning Windows for TCP/IP performance isn't specific to any one Globalscape product. Rather, it depends on which version of Windows you are using. Therefore, rather than listing the various options here, please refer to the Google search results listed here, which provides relevant links with information about.

Explanation
Receive Window Auto-Tuning popped up with Windows Vista and has been a feature of every Windows version since.
I’m going to try and explain this in a VERY oversimplified manner for the non-technical among us. If you want a good full breakdown see: The Cable Guy TCP Receive Window Auto-Tuning
https://cleverhotel.amebaownd.com/posts/17501835. Over the internet your info flows through a pipe. It does so in bunches at a time called packets. Think of it as a ball rolling through the pipe. The pipe may not be perfectly round and may change size and shape between you and your end connection be that a website or whatever.
Back in the day all OS’s used to just set the size of a packet of info and shove it into the pipe. That could either have the size of the packet needlessly small or so large it would jam up the pipe trying to squeeze itself through. Also, often the two connected computers often can send/receive data at different rates, sending too fast could lead to dropped packets (info not getting there). With every packet sent the sending computer would say “did you get that?” and the receiving computer wold say yes or no. If no the packet gets resent. This is called ACK. Obviously all this increases network traffic.
That led to Geeks tinkering with the receive window settings (RWIN) to try and max out their personal connection. It worked to some degree but not with every connection. Often the optimal setting for one connection was less than optimal for another. Then some Geeks figured out how to make the process “smart”. Your computer and the one your connected to (say, a website) now quickly figure out the maximum size of a packet that can be sent and how fast to send it.
So you see, in the vast majority of cases (like 99.999%) Receive Window Auto-Tuning is a good thing.
I hope that made sense.

Traktor pro 2 delete cue point traktor. What Microsoft Says
Microsoft Windows Networking Team – An Update on Windows TCP AutoTuningLevel

How To Enable Windows Auto Tuning Software

Windows 10: Disable auto tuning Windows 10. Discus and support Disable auto tuning Windows 10 in Windows 10 Network and Sharing to solve the problem; Can i disable auto tuning windows 10? Discussion in 'Windows 10 Network and Sharing' started by SurajitGhosh2, Oct 5, 2018.

Like all modern operating systems Windows has receive window auto-tuning to dynamically adjust the receive buffer size to the throughput and latency of the link. Disabling this feature will definitely limit your Internet speeds. Auto-tuning is consistent throughout all variants of TCP and present in all modern operating systems. In the modern Internet the range of latencies and throughput speeds that must be accommodated is simply too large to manage statically and must be adjusted dynamically. If you have changed your AutoTuningLevel to disabled, please reset it to normal in order to restore your Internet speeds…Auto-Tuning on the other hand should NEVER be disabled.

My Tests
Test Machine = Windows 10 Pro 64-bit
RED = Slower Emotional piano vst free download.

Default	Disabled
Speedtest.net (Server in Richmond VA) Ping 8ms DL 180.23 Mbps Up 12.23	Speedtest.net (Server in Richmond VA) Ping 8ms DL 180.30 Mbps Up 12.16
Fast.com 170 Mbps	Fast.com 87 Mbps
Speakeasy DL 180.27 Mbps Up 12.00 Mbps Server Washington DC	Speakeasy DL 178.99 Mbps Up 12.10 Mbps Server Washington DC
Google (https://www.google.com/#q=internet+speed+test) 170.2 Mbps download 11.9 Mbps upload Latency: 34 ms Server: Washington, DC	Google (https://www.google.com/#q=internet+speed+test) 48.8 Mbps download 11.7 Mbps upload Latency: 18 ms Server: Washington, DC

How To Enable Windows Auto Tuning Free

*Note – The slower speeds were retested several times with similar results.

Enable Windows Auto Tuning

Conclusion
In my tests his setting seems to have either no effect or a negative effect.
BAD TWEAK